Metagenomics reveals the resistance patterns of electrochemically treated erythromycin fermentation residue
作者：
Jieya Zhou;Hao Wu;Haiyan Wang;Zongru Wu;Lihu Shi;...
通讯作者：
Shulei Tian;Li-an Hou
作者机构：
State Key Laboratory of Environmental Criteria and Risk Assessment, Chinese Research Academy of Environmental Sciences, Beijing 100012, China
State Key Laboratory of Water Environment Simulation, School of Environment, Beijing Normal University, Beijing 100875, China
Inner Mongolia Autonomous Region Solid Waste and Soil Ecological Environment Technology Center, Hohhot 010020, China
High Tech. Inst. Beijing, Beijing 100085, China
通讯机构：
State Key Laboratory of Environmental Criteria and Risk Assessment, Chinese Research Academy of Environmental Sciences, Beijing 100012, China
State Key Laboratory of Water Environment Simulation, School of Environment, Beijing Normal University, Beijing 100875, China
High Tech. Inst. Beijing, Beijing 100085, China
语种：
英文
期刊：
环境科学学报(英文版)
ISSN：
1001-0742
年：
2025
卷：
148
页码：
567-578
摘要：
Erythromycin fermentation residue (EFR) represents a typical hazardous waste produced by the microbial pharmaceutical industry. Although electrolysis is promising for EFR disposal, its microbial threats remain unclear. Herein, metagenomics was coupled with the random forest technique to decipher the antibiotic resistance patterns of electrochemically treated EFR. Results showed that 95.75% of erythromycin could be removed in 2 hr. Electrolysis temporarily influenced EFR microbiota, where the relative abundances of Proteobacteria and Actinobacteria increased, while those of Fusobacteria, Firmicutes, and Bacteroidetes decreased. A total of 505 antibiotic resistance gene (AR...
