The association of isocarbophos and isofenphos with different types of glucose metabolism: The role of inflammatory cells
作者:
Jintian Geng;Dandan Wei;Lulu Wang;Qingqing Xu;Juan Wang;...
通讯作者:
Zhenxing Mao
作者机构:
Department of Epidemiology and Biostatistics, College of Public Health, Zhengzhou University, Zhengzhou 450001, China
Department of Occupational and Environmental Health Sciences, College of Public Health, Zhengzhou University, Zhengzhou 450001, China
School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430074, China
通讯机构:
Department of Epidemiology and Biostatistics, College of Public Health, Zhengzhou University, Zhengzhou 450001, China
语种:
英文
关键词:
Isocarbophos,Isofenphos,Type 2 diabetes mellitus,Inflammatory cells,Mediation effect
期刊:
环境科学学报(英文版)
ISSN:
1001-0742
年:
2025
卷:
147
页码:
322-331
摘要:
To investigate the associations between isocarbophos and isofenphos with impaired fasting glucose (IFG) and type 2 diabetes mellitus (T2DM), and to assess the mediation roles of inflammation cells. There were 2701 participants in the case-control study, including 896 patients with T2DM, 900 patients with IFG, 905 subjects with NGT. Plasma isocarbophos and isofenphos concentrations were measured using gas chromatography and triple quadrupole tandem mass spectrometry. Generalized linear models were used to calculate the relationships between plasma isofenphos and isocarbophos levels with inflammatory factor levels and T2DM. Inflammatory cell was used as mediators to estimat...